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Cerdulatinib hydrochloride

CAS No. 1369761-01-2

Cerdulatinib hydrochloride ( —— )

Catalog No. M17977 CAS No. 1369761-01-2

Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 78 Get Quote
10MG 105 Get Quote
25MG 201 Get Quote
50MG 354 Get Quote
100MG 527 Get Quote
500MG 1143 Get Quote
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Biological Information

  • Product Name
    Cerdulatinib hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively.
  • Description
    Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    c-Fms; MST1; ARK5; MLK1; Tyk2
  • Research Area
    Cancer|Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    1369761-01-2
  • Formula Weight
    482
  • Molecular Formula
    C20H28ClN7O3S
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    Cl.CCS(=O)(=O)N1CCN(CC1)C1=CC=C(NC2=NC(NC3CC3)=C(C=N2)C(N)=O)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Coffey G, J Pharmacol Exp Ther. 2014, 351(3), 538-548.
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